New insights into germ cell tumor genomics
نویسندگان
چکیده
منابع مشابه
Comparative genomics of yeast species: new insights into their biology
The genomes of two hemiascomycetous yeasts (Saccharomyces cerevisiae and Candida albicans) and one archiascomycete (Schizosaccharomyces pombe) have been completely sequenced and the genes have been annotated. In addition, the genomes of 13 more Hemiascomycetes have been partially sequenced. The amount of data thus obtained provides information on the evolutionary relationships between yeast spe...
متن کاملComparative genomics of yeast species: new insights into their biology.
The genomes of two hemiascomycetous yeasts (Saccharomyces cerevisiae and Candida albicans) and one archiascomycete (Schizosaccharomyces pombe) have been completely sequenced and the genes have been annotated. In addition, the genomes of 13 more Hemiascomycetes have been partially sequenced. The amount of data thus obtained provides information on the evolutionary relationships between yeast spe...
متن کاملNew insights into testicular germ cell tumorigenesis from gene expression profiling.
We have shown recently that about half of the human TGCTs(3) reveal DNA copy number increases affecting two distinct regions on chromosome arm 17q. To identify potential target genes with elevated expressions attributable to the extra copies, we constructed a cDNA microarray containing 636 genes and expressed sequence tags from chromosome 17. The expression patterns of 14 TGCTs, 1 carcinoma in ...
متن کاملGenome-wide expression profiling reveals new insights into pathogenesis and progression of testicular germ cell tumors.
Testicular germ cell tumors (GCT) are the most frequent malignancy in young adults and arise from intratubular germ cell neoplasia undetermined (IGCNU, also referred to as carcinoma in situ, CIS). To determine the transcriptional programs involved in the transition from normal germ cells to GCT, and to further elucidate genetic differences between seminomas and non-seminomatous GCT the global e...
متن کاملGene Expression Profiling New Insights into Testicular Germ Cell Tumorigenesis from Updated Version
We have shown recently that about half of the human TGCTs reveal DNA copy number increases affecting two distinct regions on chromosome arm 17q. To identify potential target genes with elevated expressions attributable to the extra copies, we constructed a cDNA microarray containing 636 genes and expressed sequence tags from chromosome 17. The expression patterns of 14 TGCTs, 1 carcinoma in sit...
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ژورنال
عنوان ژورنال: Andrology
سال: 2019
ISSN: 2047-2919,2047-2927
DOI: 10.1111/andr.12616